Management of sexual dysfunction in postmenopausal bc patients taking adjuvant AIs

bc and treatment effects on sexuality, fertility, menopause, mojo ....
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Janine
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Management of sexual dysfunction in postmenopausal bc patients taking adjuvant AIs

Postby Janine » Mon May 19, 2008 1:32 am



C. Derzko, MD, S. Elliott, MD, and W. Lam, BSc(Pharm) MD
Curr Oncol. 2007 December; 14(Supplement 1): S20–S40. PMCID: PMC2140180
Copyright 2007 Multimed Inc

"Treatment with aromatase inhibitors for postmenopausal women with breast cancer has been shown to reduce or obviate invasive procedures such as hysteroscopy or curettage associated with tamoxifen-induced endometrial abnormalities. The side effect of upfront aromatase inhibitors, diminished estrogen synthesis, is similar to that seen with the natural events of aging. The consequences often include vasomotor symptoms (hot flushes) and vaginal dryness and atrophy, which in turn may result in cystitis and vaginitis. Not surprisingly, painful intercourse (dyspareunia) and loss of sexual interest (decreased libido) frequently occur as well. Various interventions, both non-hormonal and hormonal, are currently available to manage these problems. The purpose of the present review is to provide the practitioner with a wide array of management options to assist in treating the sexual consequences of aromatase inhibitors. The suggestions in this review are based on recent literature and on the recommendations set forth both by the North American Menopause Association and in the clinical practice guidelines of the Society of Gynaecologists and Obstetricians of Canada." - [from the abstract]
Janine

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