Prophylactic mastectomy for the prevention of breast cancer
Lostumbo L, Carbine NE, Wallace J, Ezzo J, Dickersin K
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Women should be aware of their true risk of developing breast cancer and the limitations of current evidence when considering prophylactic mastectomy
Surgically removing both breasts to prevent breast cancer (bilateral prophylactic mastectomy or BPM) may reduce the incidence of breast cancer and improve survival in women with high breast cancer risk, but the studies have methodological limitations. After BPM, most are satisfied with their decision, but less satisfied with cosmetic results and body image. Many required additional surgeries. Most experience reduced cancer worry, but because women may overestimate their breast cancer risk, they need to understand their true risk if considering BPM. In women who have had cancer in one breast (and thus are at higher risk of developing a primary cancer in the other) removing the other breast may reduce the incidence of cancer in that other breast, but there is insufficient evidence that this improves survival.
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