Effective Oral Chemotherapy for Breast Cancer: Pillars of Strength

Information about conventional breast cancer treatments - inc surgery, chemo, rads, hormonal, reconstruction, lymphedema, side effects
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Janette
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Postby Janette » Sun Dec 14, 2008 1:26 pm

Thanks Janine,
I joined looks like a great site for information.
Janette


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Janine
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Postby Janine » Sun Dec 14, 2008 11:05 am

hmmm... perhaps you need to register with medscape - it's free.
Janine

Mereana
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Hi Jennifer

Postby Mereana » Sun Dec 14, 2008 9:10 am

I managed to get in by pushing on the "read more" link at the end of the abstract Janine gave.Good luck. xxxxxx
Dx Apr 07,Mets Oct 07,Her2+ Hormone neg,AC,Rads,taxol,Herceptin,Xeloda,Bonefos,Zometa,Tykerb,Oxycontin,new mets Jan08,Oct08,Dec08,May09,July09 bones and spleen.

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cherub
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Postby cherub » Sun Dec 14, 2008 8:10 am

hey jan
cant get to the link as it needs a password
:heart:
Jennifer
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Primary BC:
DX Apr 06 DCIS Gr3 St2B Oes + Prog + Lump & Aux 1 node+
TX: ECx4, Radio 6.5wks, Port, Taxol x12 & AI'S & have CFS
ABC:
October 08 Mets spine & Chest wall
Dec 08 mets liver - taxotere, xoleda & zometa
Jan 09 PPort - now still on Taxotere 18months
Mediastinum mets are taking my voice away
now for rads x 10 august 2010

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Janine
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Effective Oral Chemotherapy for Breast Cancer: Pillars of Strength

Postby Janine » Sat Dec 13, 2008 11:02 pm

- very heavy going but some useful information about the oral chemos if you can plough through it.

From Annals of Oncology

Effective Oral Chemotherapy for Breast Cancer: Pillars of Strength
Posted 05/21/2008
M. Findlay; G. von Minckwitz; A. Wardley
Abstract
Traditionally, anticancer therapy has been dominated by intravenous drug therapy. However, oral agents provide an attractive approach to chemotherapy and use of oral treatments is increasing. We discuss the benefits and challenges of oral chemotherapy from the perspectives of patients, healthcare providers and healthcare funders. Important issues include patient preference, efficacy, compliance, bioavailability, reimbursement, use in special patient populations, financial and staff time savings and flexibility of dosing. We review data for traditional oral agents (e.g. cyclophosphamide, methotrexate), newer oral chemotherapies (e.g. capecitabine), oral formulations of traditionally intravenous agents (e.g. vinorelbine, idarubicin) and new biologic agents under evaluation in breast cancer (e.g. tyrosine kinase inhibitors). Lastly, we review studies of all-oral combination regimens. The wealth of data available and the increasing use of oral agents in breast cancer suggest that many of the concerns and perceptions about oral therapy, including efficacy and bioavailability, have been overcome, and that oral therapy will play a major role in breast cancer management in the future in both the metastatic and adjuvant settings.
Janine



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